Research Associate-Fixed Term
Michigan State University

Job no: 706742
Work type: Faculty/Academic Staff
Major Administrative Unit / College: College Of Natural Science
Department: Biochemistry & Molecular Biology Cns 10032098
Sub Area: FAS- Fac./Acad Staff
Salary: Salary Commensurate with Experience
Location: East Lansing
Categories: Research/Scientific, Fixed Term Academic Staff, Full Time (90-100%), Non-Union
Position Summary

A postdoctoral research associate position in structural biology is immediately available in the Hu lab at the Department of Biochemistry & Molecular Biology, Michigan State University. By deploying approaches of structural biology (primarily x-ray crystallography), biochemistry, biophysics, and cell biology, my group has been working on multiple macromolecules important in biomedicine and biotechnology, including the ZIP metal transporters (Nat Commun. 2016, 7:11979; Sci Adv. 2017, 3:e1700344; Cell Rep. 2020, 31:107582), the PIPK lipid kinases (Sci Adv. 2016, 2:e1600925; Biochem J. 2018, 475:2257), and the LarA racemases/epimerases (Science. 2015, 349:66; PNAS. 2017, 114:9074). For more information, please visit https://bmb.natsci.msu.edu/faculty/jian-hu/.

The recently opened and fully functional MSU cryo-EM facilities have a 200 kV Talos Arctica microscope equipped with a Falcon 3 direct detection detector, phase plate, and autoloader. The facilities provide state-of-the-art computational resources, training for students and postdocs, and opportunities for collaboration with the core faculty members. More information can be found at https://cryo-em.natsci.msu.edu/equipment/cryo-em-facility/. Additional microscopes complementary to the facilities are available in The Center for Advanced Microscopy (https://cryo-em.natsci.msu.edu/equipment/center-for-advanced-microscopy/).

Description of duties: Single-particle cryo-EM will be applied to the suitable systems which have been identified in the ongoing projects to clarify the working mechanisms at atomic resolution through a combination of biochemical, biophysical and cell biological approaches.

The successful candidate is expected to be highly self-motivated with Ph.D. in structural biology, biochemistry, biophysics, or related fields. Hands-on experience and a proven track record in single-particle cryo-EM is required. Experience in large scale eukaryotic protein expression/purification, ideally using mammalian cell expression system, is desirable. Experience in membrane protein study is a plus but not a must.

Equal Employment Opportunity Statement

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, citizenship, age, disability or protected veteran status.

Required Degree

Doctorate -Structural Biology, Biochemistry, Biophy

Minimum Requirements

Ph.D. in structural biology, biochemistry, biophysics, or related fields; hands-on experience and a proven track record in single-particle cryo-EM are required.

Desired Qualifications

Experience in large scale eukaryotic protein expression/purification, ideally using mammalian cell expression system, is desirable. Experience in membrane protein study is a plus but not a must.

Required Application Materials

Cover letter, CV, names and contact information for three professional references.

Review of Applications Begins On

06/04/2021

Website

https://bmb.natsci.msu.edu/

MSU Statement

Michigan State University has been advancing the common good with uncommon will for more than 160 years. One of the top research universities in the world, MSU pushes the boundaries of discovery and forges enduring partnerships to solve the most pressing global challenges while providing life-changing opportunities to a diverse and inclusive academic community through more than 200 programs of study in 17 degree-granting colleges.

Advertised: May 21, 2021 Eastern Daylight Time
Applications close: May 21, 2023 Eastern Daylight Time